Note: CCIR academic staffs’ name are highlighted with blue.



Published Conference Abstract in 2013


1.

Baosheng  Guo, Baoting Zhang, Jun Wang, Chao Liang, Heng Wu, Zhijun Yang, Albert H. L.  Chow, Zhibo Hou, Yadong Huang, Fuchu He, Ling Qin, Lingqiang Zhang, Zhaoxiang  Bian, Aiping Lu, Ge Zhang. (Asp-Ser-Ser)6 facilitates bone anabolic siRNA  specifically targeting osteogenic cells in aged ovariectomized rats. 2013  Orthopaedics Research Society Annual Meeting. San Antonio, Texas. January  26–29, 2013 (http://www.ors.org/Transactions/59/PS2--082/1465.html).

2.

Baosheng  Guo, Xiaogang Wang, An Hong, Aiping Lu, Baoting Zhang, Ge Zhang. Therapeutic  inhibition of miR-214 within osteogenic cells in aged osteoporotic rats  induced by ovariectomy for bone anabolic strategy: Optimization of dosage and  duration. Bone Joint J 2014 vol. 96-B no. SUPP 11. 8th Combined Meeting of  Orthopaedic Research Societies. San Servolo Venice, Italy. October 13-16,  2013.

3.

Baosheng  Guo, Xiaogang Wang, An Hong, Aiping Lu, Baoting Zhang, Ge Zhang. Therapeutic  silencing intra-osseous PLEKHO1 for promoting bone formation in a rat model  of aged postmenopausal osteoporosis. RNAi China, 2013. Kunshan, China. June  20-22, 2013.

4.

Bing  He, Jin Liu, Tao Tang, Baosheng Guo, Xiaohua Pan, Aiping Lu and Ge Zhang.  Potential strategy regulating miRNAs to improve impaired fracture healing in  aged females: A systematic view for timing and targets. Bone Joint J. 2014  vol. 96-B no. SUPP 11 207. 8h Combined Meeting of Orthopaedic Research  Societies. San Servolo Venice, Italy. October 13-16, 2013.

5.

Jin  Liu, Baosheng Guo, Yixin He, Xiaohua Pan, Lei Dang, Lingqiang Zhang, Aiping  Lu, Ge Zhang. Could casein kinase-2 interacting protein-1 (CKIP-1) be  postulated as a molecular target for promoting aged fracture repair in  females? JOURNAL OF BONE AND MINERAL RESEARCH. Vol. 28. Suppl. 1. 2013  American Society of Bone and Mineral Research Annual Meeting. Baltimore,  Maryland, USA. October 4–7, 2013.



Published Conference Abstract in 2014


6.

Xiaojuan  He, Kang Zheng, Yukun Zhao, Baosheng Guo, Jin Liu, Ge Zhang, Aiping Lu.  Aberrant overexpression of CKIP-1 in osteoblast correlated with progressive  bone erosion and decreased bone formation in collagen-induced arthritis of  mice. 7th International Conference on Osteoporosis and Bone Research, 2014.  Xiamen, China. October 16-19, 2014 (Accepted).

7.

Baosheng  Guo, Aiping Lu, Baoting Zhang, Ge Zhang. Inhibition of miR-214 by  (Asp-Ser-Ser)6-liposome capsulated antagomiR-214 in osteogenic cells of aged  osteoporotic rats: Quantification analysis for expression levels of miR-214,  osteocalcin mRNA and ATF4 protein in osteogenic cells. 2014 American  Orthopaedics Society Annual Meeting, New Orleans, Louisiana March 15-18  (http://www.ors.org/Transactions/60/0604.pdf).

8.

Baosheng  Guo, Heng Wu, Lingqiang Zhang, Aiping Lu, Baoting Zhang, Ge Zhang. Therapeutic silencing intra-osseous Plekho1 for promoting bone formation in a  rat model of aged postmenopausal osteoporosis  (http://www.ors.org/Transactions/60/0566.pdf). 2014 American Orthopaedics  Society Annual Meeting, New Orleans, Louisiana March 15-18.

9.

Baosheng  Guo, Jin Liu, Heng Wu, Lingqiang Zhang, Ling Qin, Aiping Lu, Baoting Zhang, Ge Zhang. Ckip-1 in osteoblasts plays an inhibition role in bone formation in  aged male osteoporosis. MOLECULAR THERAPY. Vol. 22. Suppl.1 S39-S40. American  Society of Gene & Cell Therapy 17th Annual Meeting. Washingon, DC. May  21-24, 2014.

10.

Baosheng  Guo, Liu Jin, Dang lei, Liang Chao, Xiaohua Pan, Lingqiang Zhang, Aiping Lu,  Baoting Zhang, Ge Zhang. Up-regulated CKIP-1 expression within osteoblasts  associates with reduced BMP signaling and decreased bone formation during  aging. 5th Sino-American Symposium on Clinical and Translational Medicine  (SAS-CTM). Beijing, China. June 21-22, 2014.

11.

Baosheng  Guo, Liu Jin, Heng Wu, Dang lei, Lingqiang Zhang, Aiping Lu, Baoting Zhang,  Ge Zhang. Therapeutic silencing intra-osseous Ckip-1 for promoting bone  formation in an aged rat model of male osteoporosis. ASBMR 2014 Annual  Meeting. Houston, Texas. September 12-15, 2014.

12.

Baosheng  Guo, Liang Chao, Xiaohua Pan, Lingqiang Zhang, Aiping Lu, Baoting Zhang, Ge  Zhang. Up-regulated CKIP-1 expression within osteoblasts associates with  reduced BMP signaling and decreased bone formation during aging. 7th  International Conference on Osteoporosis and Bone Research, 2014. Xiamen,  China. October 16-19, 2014 (Accepted).

13.

Defang  Li, Chao Liang, Baosheng Guo, Jin Liu, Lei Dang, Liang Xu, Xiaojuan He, Zicai  Liang, Aiping Lu, Ge Zhang. DNM3 Participates in Exosome-Mediated miR-214  Transfer From Differentiating Osteoclasts To Regulate Osteoblastic Activity:  In Vitro Evidences. MOLECULAR THERAPY. Vol. 22. Suppl.1 S158-S158. American  Society of Gene & Cell Therapy 17th Annual Meeting. Washingon, DC. May  21-24, 2014.

14.

Defang  Li, Chao Liang, Baosheng Guo, Jin Liu, Lei Dang, Liang Xu, Xiaojuan He, Zicai  Liang, Aiping Lu, Ge Zhang. Exosome-encapsulated miR-214 secreted from  osteoclast to inhibit osteoblastic activity. ASBMR 2014 Annual Meeting.  Houston, Texas. September 12-15, 2014 (Accepted).

15.

Biao  Liu, Xiaojuan He, Ge Zhang, Aiping Lu. A novel triptolide-nucleolin aptamer  conjugate (TMPC001) with super antitumor activity on advanced pancreatic  cancer. Planta Med 2014; 80 - CL26 DOI: 10.1055/s-0034-1382359.

16.

Biao  Liu, Baosheng Guo, Xiaojuan He, Defang Li , Ge Zhang, Aiping Lu. A novel  Triptolide-Nucleolin aptamer conjugate with super antitumor activity on  advanced pancreatic cancer cell in vitro. MOLECULAR THERAPY. Vol. 22. Suppl.1  S221-S221. American Society of Gene & Cell Therapy 17th Annual Meeting.  May 21-24, 2014.

17.

Chao  Liang, Baosheng Guo, Heng Wu, Lingqiang Zhang, Aiping Lu, Ge Zhang. Aptamer-Functionalized Lipid Nanoparticles (LNPs) Targeting Osteoblasts as a  Novel RNA Interference-Based Bone Anabolic Strategy. ASBMR 2014 Annual  Meeting. Houston, Texas. September 12-15, 2014 (Accepted).

18.

Chao  Liang, Baosheng Guo, Heng Wu, Lingqiang Zhang, Aiping Lu, Ge Zhang.  Aptamer-Functionalized Lipid Nanoparticles (LNPs) Targeting Osteoblasts as a  Novel RNAi-Based Bone Anabolic Strategy. 5th Sino-American Symposium on  Clinical and Translational Medicine (SAS-CTM). Beijing, China. June 21-22,  2014.

19.

Chao  Liang, Baosheng Guo, Heng Wu, Lei Dang, Zhijun Yang, Lingqiang Zhang, Aiping  Lu, Ge Zhang. Development of aptamer-functionalized osteoblast-targeting  lipid nanoparticles encapsulating osteogenic siRNAs for bone anabolic  therapy: investigation of tissue-selective distribution, dose-response  pattern and persistence of gene silencing. Orthopaedic Research Society (ORS)  2014 annual meeting. March 15-18, 2014  (http://www.ors.org/Transactions/60/1160.pdf).  

20.

Chao  Liang, Baosheng Guo, Heng Wu, Lingqiang Zhang, Aiping Lu, Ge Zhang. Aptamer-functionalized lipid nanoparticles (LNPs) targeting osteoblasts as a  novel RNA interference (RNAi)-based bone anabolic strategy. The 7th  International Conference on Osteoporosis and Bone Research (ICOBR 2014).  October 16-19, 2014 (Accepted).

21.

Chao  Liang, Baosheng Guo, Heng Wu, Lingqiang Zhang, Aiping Lu, Ge Zhang.  Aptamer-functionalized delivery system for osteogenic siRNAs to achieve  osteoblast-specific RNA interference for bone anabolic therapy. Orthopaedic  Research Society (ORS) 2015 annual meeting. Xiamen, China. March 28-31, 2015  (Submitted).

22.

Lei  Dang, Baosheng Guo, Defang Li, Aiping Lv, Ge Zhang. A delivery system  specifically approaching bone resorption surfaces to facilitate therapeutic  modulation of miRNAs in osteoclasts. MOLECULAR THERAPY. Vol. 22. Suppl.1.  S131-S131. American Society of Gene & Cell Therapy (ASGCT) 2014 annual  meeting, Washington, USA. May 21-24, 2014.

23.

Lei  Dang, Baosheng Guo, Defang Li, Jin Liu, Chao Liang, Xiaojuan He, Heng Wu,  Zhijun Yang, Zicai Liang, Aiping lu, Ge Zhang. A peptide-modified delivery  system specifically approaching bone resorption surfaces for therapeutic  modulation of miRNAs in osteoclasts. American Society for Bone and Mineral  Research (ASMBR) 2014 annual meeting, Houston, USA, September 12-15, 2014.

24.

Lei  Dang, Baosheng Guo, Defang Li, Jin Liu, Chao Liang, Xiaojuan He, Heng Wu,  Zhijun Yang, Zicai Liang, Aiping lu, Ge Zhang. A delivery system to approache  bone resorption surfaces for specifically targeting osteoclasts in vivo.  Orthopaedic Research Society (ORS) 2015 annual meeting, Las Vegas, USA, March  24-28, 2015 (Submitted).




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