• About the Lab
  • Technician
  • Equipment
  • Protocol




The Histopathology & Bio-imaging Lab provides techniques, equipment and protocols for bio-imaging and non-destructive 3-D imaging evaluation as well as histopathological examination and histomorphometric analysis for musculoskeletal research and for developing innovative drugs in bone and joint diseases. So far, the lab has established the following techniques.


Ø  Biophotonic-based Fluorescence Imaging Techniques

Lumina XR Series III could sensitively image bioluminescent / fluorescent reporters and differentially evaluate their distribution in various organs within the same animal. It is employed to examine drug delivery by in vivo bio-imaging analysis.


Ø  Histopathological Examination & Histomorphometric Analysis & Gene Expression Analysis in
    specific cells

Non-decalcified histological processing for bone tissue and static / dynamic bone histomorphometric analysis could be performed in the lab. Techniques of wide special stains for bone and cartilage, such as the VonKossa, tartrate-resistant acid phosphatase (TRAP), alkaline phosphatase, Gömöritrichrome, safranin O and toluidine blue stains are provided in the lab. Further, laser-captured micro-dissection in combination with Q-PCR analysis for gene expression in specific cells is also established in the lab.