The 2017 Shanghai-Zhejiang Obesity Conference was successfully completed in Ningbo on August 20^th, 2017. This conference aimed at facilitating the development of basic understanding and therapeutic approach to obesity as well as osteoporosis. Prof. Ge Zhang was invited to attend this academic summit and give a speech entitled “From Precision Medicine to Drug Discovery: Inhibition of Osteoblastic Smurf1 Promotes Bone Formation in Distinctive Individuals with Age-related Osteoporosis”.