- 簡歷
- 研究
- 成員
- 文章著作
呂愛平教授
中醫藥學院院長
黃英豪博士中醫藥講座教授；骨與關節疾病轉化醫學研究所所長；岑堯寬岑碧泉紀念癌症炎症研究中心主任
呂愛平教授在江西中醫學院取得中醫藥學士學位，並在中國中醫研究院（現稱中國中醫科學院）取得碩士和博士學位。呂教授其後加入中國中醫科學院擔任研究工作，曾任中國中醫科學院基礎理論研究所所長及該院中醫臨床基礎醫學研究所常務副所長。二零零二至二零零六年期間，他在國家四大中醫藥工程研究中心之一的中藥固體製劑國家工程研究中心擔任領導。呂教授也被邀擔任多間大學的訪問學人，包括瑞典隆德大學、俄亥俄州立大學、香港理工大學和香港科技大學。
張戈博士
技術開發部主任;
教學科研部副主任、副教授；骨與關節疾病轉化醫學研究所副所長;
骨科基礎研究與臨床轉化應用專家
張戈博士於2000年至2003年在上海中醫藥大學與香港中文大學骨傷科臨床醫學博士聯合培養計畫下接受研究與臨床訓練，於2003年獲得骨傷科臨床醫學博士學位。自2004年至2006年，張戈博士開始在香港中文大學矯形外科及創傷學系從事博士後研究，並於2007年開始在該系受聘為研究助理教授。2012年，張戈博士正式加入香港浸會大學，參與組建香港浸會大學骨關節病轉化醫學研究所。張戈博士的研究興趣主要集中在骨質疏鬆、骨壞死、骨折修復、骨性關節炎、類風濕性關節炎等骨科疾病的基礎科學研究與臨床轉化應用研究，分別在Nature Medicine、Arthritis & Rheumatism、Journal of Bone & Mineral Research、Bone、Osteoporosis International等骨科核心期刊發表研究結果，具體資訊可以瀏覽張戈博士的實驗室主頁 (http://www.gezhanglab.com/index.php) 。
呂院長及張博士一直致力研究中醫藥治療自身免疫性疾病如類風濕性關節炎、中醫診治標準化、中醫與疾病治療果效和新藥研發等，主持多項重要的課題研究，如國家自然科學基金項目，國家十一五支撐計劃項目等等，曾發表超過三百篇研究論文，並擁有四十多項專利權。呂院長及張博士被視為中醫藥診治標準化領域之重要代表，正因其工作及研究成績斐然，多年來獲獎無數，如在2010中華中醫藥學會科技進步獎二等獎、江西省科技進步獎、2009年北京科技進步獎三等獎等等。
研究項目
項目 1 | Title: Therapeutic RNAi targeting CKIP-1 to reverse severe postmenopausal osteoporosis Principal Investigator: Dr. Ge Zhang (M.D.) Funding Body: Hong Kong General Research Fund Project ID: HKBU 479111 Exercise Year: 2011/2012 Approved Project Duration: 30 months Project Fund: HK$ 920,000 Coordinator: Dr. Baosheng Guo (Ph.D.) |
項目 2 | Title: Toward an emerging paradigm of network medicine: An innovative platform to combinational herbs / compounds-based drug discovery for complex diseases Principal Investigator: Prof. Aiping Lu (M.D., Ph.D.) Funding Body: Interdisciplinary Research Matching Scheme (IRMS) of Hong Kong Baptist University Project ID: RC-IRMS/12-13/02 Exercise Year: 2012/2013 Approved Project Duration: 24 months Project Fund: HK$ 3,000,000 Coordinator: Dr. Guang Zheng (Ph.D.) |
項目 3 | Title: Skeletal role of CK2-interating Protein-1 in Regulating Osteoblastic Bone Formation: Molecular Mechanism and Reversing Osteoporosis Principal Investigator: Dr. Ge Zhang (M.D.) Funding Body: Research Grants Council & Natural Science Foundation Council Project ID: N_HKBU435/12 Exercise Year: 2012/2013 Approved Project Duration: 48 months Project Fund: HK$ 753,925 Coordinator: Dr. Baosheng Guo (Ph.D.) |
項目 4 | Title: Study on molecular mechanism of bone formation reduction in aged women: Functional role of CKIP-1 Principal Investigator: Dr. Ge Zhang (M.D.) Funding Body: Natural Science Foundation Council Project ID: NSFC 81272045 Exercise Year: 2012/2013 Approved Project Duration: 36 months Project Fund: RMB 700,000 Coordinator: Dr. Baosheng Guo (Ph.D.) |
項目 5 | Title: Toward a novel bone anabolic strategy for aged postmenopausal osteoporosis: Inhibiting miR-214 inosteogenic cells for promoting bone formation Principal Investigator: Dr. Ge Zhang (M.D.) Funding Body: Hong Kong General Research Fund Project ID: HKBU 478312 Exercise Year: 2012/2013 Approved Project Duration: 30 months Project Fund: HK$ 950,000 Coordinator: Dr. Baosheng Guo (Ph.D.) |
項目 6 | Title: Development of aptamer-conjugated Triptolide specifically targeting synovial cell Principal Investigator: Dr. Ge Zhang (M.D.) Funding Body: Institute of Basic Research in Clinical Medicine, China Academy of Chinese Medical Sciences (Contract Study) Project ID: SCM-2012-CR-001 Exercise Year: 2012/2013 Approved Project Duration: N/A Project Fund: RMB 500,000 Coordinator: Ms. Lei Dang (B.Sc.) |
項目 7 | Title: Screening on anti-rheumatic herbal medicines Principal Investigator: Dr. Aiping Lu (M.D., Ph.D.) Funding Body: Hong Kong Baptist University Project ID: 33-12-903 Exercise Year: 2012/2013 Approved Project Duration: 24 months Project Fund: HK$ 1,000,000 Coordinator: Dr. Cheng Lu (Ph.D.) |
項目 8 | Title: Does aberrantly overexpressed casein kinase-2 interacting protein-1 contribute to failure of osteoblast-mediated repair for bone erosion in rheumatoid arthritis? Principal Investigator: Dr. Aiping Lu (M.D., Ph.D.) Funding Body: Kunshan RNAi Institute (Contract Study) Project ID: N/A Exercise Year: 2013/2014 Approved Project Duration: 36 months Project Fund: RMB 3,000,000 Coordinator: Dr. Xiaojuan He (M.D.) |
項目 9 | Title: Understanding the molecular mechanism in failure of osteoblast-mediated repair for articular bone erosion during progressive rheumatoid arthritis: Role of casein kinase-2 interacting protein-1 in controlling osteoblast function Principal Investigator: Prof. Aiping Lu (M.D., Ph.D.) Funding Body: Research Grants Council Project ID: HKBU 261113 Exercise Year: 2013/2014 Approved Project Duration: 24 months Project Fund: HK$ 606,223 Coordinator: Dr. Xiaojuan He (M.D.) |
項目 10 | Title: Aptamer-functionalized Osteoblast-targeting Delivery System for Osteogenic siRNAs to Achieve Cell-specific RNA interference for Bone Anabolic Therapy Principal Investigator: Dr. Ge Zhang (M.D.) Funding Body: Research Committee of Hong Kong Baptist University Project ID: FRG2/12-13/027 Exercise Year: 2013/2014 Approved Project Duration: 24 months Project Fund: HK$ 135,000 Coordinator: Mr. Chao Liang (M.S.) |
項目 11 | Title: Metabolomics Analysis of Chinese Medicine in Epidemic Encephalitis B prevention and treatment Principal Investigator: Dr. Ge Zhang (M.D.) Funding Body: Institute of Basic Research in Clinical Medicine, China Academy of Chinese Medical Sciences (Contract Study) Project ID: SCM-2013-CR-001 Exercise Year: 2013~ Approved Project Duration: N/A Project Fund: RMB 500,000 Coordinator: Ms. Lei Dang (B.S.) |
項目 12 | Title: Establishing the bridge for translating cell-specific RNA interference to bone anabolic therapy: An aptamer-functionalized osteoblast-targeting delivery system for osteogenic siRNAs Principal Investigator: Dr. Ge Zhang (M.D.) Funding Body: Science and Technology Innovation Commission of Shenzhen Municipality Project ID: SCM-2013-SZTIC-001 Exercise Year: 2013/2014 Approved Project Duration: 24 months Project Fund: RMB 300,000 Coordinator: Mr. Chao Liang (M.S.) |
項目 13 | Title: Research and development of triptolide-aptamer drug Principal Investigator: Prof. AipingLu (M.D., Ph.D.) Funding Body: National Science and Technology Major Projects for "major New Drugs Innovation and Development" Project ID: 2013ZX09301307 Exercise Year: 2013/2015 Approved Project Duration: 36 months Project Fund: RMB 1,500,000 Coordinator: Dr. Xiaojuan He (M.D.) |
項目 14 | Title: A unique platform for drug discovery of combinational drugs / Chinese herbal medicines / compounds Principal Investigator: Prof. Aiping Lu (M.D., Ph.D.) Funding Body: Hong Kong Baptist University Strategic Development Fund Project ID: SDF13-1209-P01 Exercise Year: 2014/2017 Approved Project Duration: 36 months Project Fund: HK$ 3,000,000 Coordinator: Dr. Guang Zheng (Ph.D.) |
項目 15 | Title: Role of MiR-214 within Osteoclast in Regulating Osteoblastic Bone Formation Principal Investigator: Dr. Ge Zhang (M.D.) Funding Body: Research Committee of Hong Kong Baptist University Project ID: FRG2/13-14/006 Exercise Year: 2014/2016 Approved Project Duration: 24 months Project Fund: HK$ 135,000 Coordinator: Dr. Defang Li (Ph.D.) |
項目 16 | Title: The Development of Chinese Medicine Clinical Practice Guidelines in Hong Kong Principal Investigator: Prof. Aiping LU (M.D., Ph.D.) & Prof. Zhaoxiang BIAN (M.D., Ph.D.) Funding Body: Hospital Authority Project ID: HA 820/126/19/19/14/6/12/1 Exercise Year: 2013/2014 Approved Project Duration: 15 months Project Fund: HK$ 444,320 Coordinator: Ms. Nannan Shi (M.Phil.) |
項目 17 | Title: Cell-specific Aptamer Facilitates Triptolide Selectively Targeting Fibroblast-like Synoviocytes and Specifically Reducing Exposure to Liver Cells Principal Investigator: Prof. Aiping LU (M.D., Ph.D.) Funding Body: Research Committee of Hong Kong Baptist University Project ID: 30-12-286 Exercise Year: 2013/2014 Approved Project Duration: 18 months Project Fund: HK$ 131,100 Coordinator: Dr. Cheng Lu (Ph.D.) |
項目 18 | Title: Role of miR-214 from Osteoclast in Regulating Osteoblastic Bone Formation Principal Investigator: Dr. Ge Zhang (M.D.) Funding Body: Interdisciplinary Research Matching Scheme (IRMS) of Hong Kong Baptist University Project ID: RC-IRMS/13-14/02 Exercise Year: 2014/2015 Approved Project Duration: 24 months Project Fund: HK$ 2,981,576 Coordinator: Dr. Defang Li (Ph.D.) |
項目 19 | Title: Aptamer-functionalized osteoblast-targeting delivery system for osteogenic siRNAs to achieve cell-specific RNA interference for bone anabolic therapy Principal Investigator: Dr. Ge Zhang (M.D.) Funding Body: Hong Kong General Research Fund (GRF) Project ID: 12102914 Exercise Year: 2014/2015 Approved Project Duration: 36 months Project Fund: HK$ 1,035,000 Coordinator: Mr. Chao Liang (M.S.) |
項目 20 | Title: Characterization of Linkage between Symbiotic Gut Microbes and Fatty Acid Metabolism in Rheumatoid Arthritis Patients Principal Investigator: Prof. Aiping LU (M.D., Ph.D.) & Prof. Cai Zongwei (Ph.D.) Funding Body: Interdisciplinary Research Matching Scheme (IRMS) of Hong Kong Baptist University Project ID: RC-IRMS/13-14/03 Exercise Year: 2014/2015 Approved Project Duration: 24 months Project Fund: HK$ 2,944,160 Coordinator: Dr. Cheng Lv (Ph.D.) |
項目 21 | Title: Toward Targeted Therapy In Advanced Pancreatic Cancer: A Smart Triptolide-Nucleolin Aptamer Conjugate (UIM/256) Principal Investigator: Prof. Aiping Lu Funding Body: Hong Kong Innovation and Technology Fund Project ID: UIM/256 Exercise Year: 2014/2016 Approved Project Duration: 24 months Project Fund: HK$ 2,339,560 Coordinator: Mr. Biao Liu (M.S.) |
項目 22 | Title:Toward Cell-targeted Therapeutics in Osteosarcoma: a Smart Triptolide-aptamer Conjugate Principal Investigator: Prof. Aiping Lu (M.D., Ph.D.) and Prof. Dean Guo (Ph.D.) Funding Body: Croucher Foundation Project ID: Gnt#CAS14BU/CAS14201 Exercise Year: 2014/2016 Approved Project Duration: 36 months Project Fund: HK$ 1,200,000 Coordinator: Dr. Defang Li (Ph.D.) and Mr. Chao Liang (M.S.) |
◆ 研究助理教授
◆ 專業：癌症及代謝病的分子病理研究及治療標靶，系統生物學，抗癌及抗高血脂的藥物開發
◆ 電郵: wcstai@hkbu.edu.hk
◆ 研究助理教授
◆ 專業：臨床骨科
◆ 電郵: borisguo@hkbu.edu.hk
◆ 博士生
◆ 專業：骨科
◆ 電郵：drlausums@gmail.com
◆ 博士生
◆ 專業： 分子與細胞生物學
◆ 電郵：liangchao512@163.com
◆ 博士生
◆ 專業： 藥理學
◆ 電郵： liubiao@hkbu.edu.hk
◆ 博士生
◆ 專業：生物信息
◆ 電郵：hebinghb@gmail.com
陳秉道
◆ 博士生
◆ 專業：分子生物學
◆ 電郵：11467363@life.hkbu.edu.hk
Impact Factor>=9 (Journal Citation Report 2014)
1 | Wang X, Guo B, Li Q, Peng J, Yang Z, Wang A, Li D, Hou Z, Lv K, Kan G, Cao H, Wu H, Song J , Pan X, Sun Q, Ling S, Li Y, Zhu M, Zhang P, Peng S, Xie X, Tang T, Hong A, Bian Z, Bai Y, Lu A, Li Y, He F, Zhang G (Corresponding Author), Li Y(Corresponding Author). miR-214 targets ATF4 to inhibit bone formation. Nat Med. 2013 Jan;19(1):93-100. |
2. | Zhang G (Corresponding Author), Guo B, Wu H, Tang T, Zhang BT, Zheng L, He Y, Yang Z, Pan X, Chow H, To K, Li Y, Li D,Wang X, Wang Y, Lee K, Hou Z, Dong N, Li G, Leung K, Hung L, He F, Zhang L (Corresponding Author), Qin L (Corresponding Author). A delivery system targeting bone formation surfaces to facilitate RNAi-based anabolic therapy. Nat Med. 2012 Jan 29;18(2):307-14. |
5=<Impact Factor<9 (Journal Citation Report 2014)
1. | Wang S, Wei X, Zhou J, Zhang J, Li K, Chen Q, Terek R, Fleming BC, Goldring MB, Ehrlich MG, Zhang G, Wei L. Identification of Alpha 2 Macroglobulin (A2M) as a master inhibitor of cartilage degrading factors that attenuates post-traumatic osteoarthritis progression. Arthritis Rheumatol. 2014 Feb 27 |
2. | Zhang Z, Lu C (Co-first author), Liu X, Su J, Dai W, Yan S, Lu A, Zhang W. Global and Targeted Metabolomics Reveal that Bupleurotoxin, a Toxic Type of Polyacetylene, Induces Cerebral Lesion by Inhibiting GABA receptor in Mice. J Proteome Res. 2013 Dec 16. [Epub ahead of print] |
3. | Shek Man Chim, Jennifer Tickner, Siu To Chow, Vincent Kuek, Baosheng Guo, Ge Zhang, Vicki Rosen, Wendy Erber, Jiake Xu. Angiogenic factors in bone local environment. Cytokin Growth Factor Rev. 2013 Apr 20. doi:pii: S1359-6101(13)00028-2.10.1016/j.cytogfr. 2013.03.008. [Epub ahead of print] |
4. | Huang C, Zheng C, Li Y, Wang Y, Lu A, Yang L. Systems pharmacology in drug discovery and therapeutic insight for herbal medicines. Brief Bioinform. 2013 Jun 3. [Epub ahead of print] |
5. | Chen SH, Wang XL, Xie XH, Zheng LZ, Yao D, Wang DP, Leng Y, Zhang G (Corresponding Author), Qin L (Corresponding Author). Comparative study of osteogenic potential of a composite scaffold incorporating either endogenous bone morphogenetic protein-2 or exogenous phytomolecule icaritin: an in vitro efficacy study. Acta Biomater. 2012 Aug;8(8):3128-37 |
6. | Xie XH, Wang XL, He YX, Liu Z, Sheng H, Zhang G (Corresponding Author), Qin L (Corresponding Author). Promotion of bone repair by implantation of cryopreserved bone marrow-derived mononuclear cells in a rabbit model of steroid-associated osteonecrosis. Arthritis Rheum. 2012 May; 64(5):1562-71 |
7. | Tan Y, Li J, Liu X, Ko J, He X, Lu C, Liu Z, Zhao H, Xiao C, Niu X, Zha Q, Yu Z, Zhang W, Lu A (Corresponding Author). Deciphering the differential toxic responses of Radix aconiti lateralis praeparata in healthy and hydrocortisone-pretreated rats based on serum metabolic profiles. J Proteome Res. 2013 Jan 4; 2(1):513-24. |
8. | Zhang C, Jiang M, Lu A (Corresponding Author). Considerations of traditional Chinese medicine as adjunct therapy in the management of ulcerative colitis. Clin Rev Allergy Immunol. 2013 Jun;44(3):274-83. |
9. | Zhao L, Nicholson JK, Lu A, Wang Z, Tang H, Holmes E, Shen J, Zhang X, Li JV, Lindon JC. Targeting the human genome-microbiome axis for drug discovery: inspirations from global systems biology and traditional Chinese medicine. J Proteome Res.2012 Jul 6;11(7):3509-19. |
10. | Zhang G, Sheng H, He YX, Xie XH, Wang YX, Lee KM, Yeung KW, Li ZR, He W, Griffith JF, Leung KS, Qin L. Continuous occurrence of both insufficient neovascularization and elevated vascular permeability in rabbit proximal femur during inadequate repair of steroid-associated osteonecrotic lesions. Arthritis Rheum. 2009 Oct; 60(10):2966-77. |
11. | Zhang G, Qin L, Shi Y. Epimedium-derived phytoestrogen flavonoids exert beneficial effect on preventing bone loss in late postmenopausal women: a 24-month randomized, double-blind and placebo-controlled trial. J Bone Miner Res. 2007 Jul;22(7):1072-9. |
Impact Factor<5 (Journal Citation Report 2014)
1. | Xuyan Niu., Cheng Lu., Cheng Xiao., Zhiguo Zhang, Miao Jiang, Dan He,Yanqin Bian4, Ge Zhang, Zhaoxiang Bian, Aiping Lu.The Shared Crosstalk of Multiple Pathways Involved in the Inflammation between Rheumatoid Arthritis and Coronary Artery Disease Based on a Digital Gene Expression Profile.Plos One.DOI:10.1371/journal.pone.0113659 December 16, 2014 |
2. | Protein Kinase C Inhibitor, GF109203X Attenuates Osteoclastogenesis, Bone Resorption and RANKL-induced NF-κB and NFAT activity. Yao J, Li J, Zhou L, Cheng J, Chim SM, Zhang G, Quinn JM, Tickner J, Zhao J, Xu J.J Cell Physiol. 2014 Nov 3. doi: 10.1002/jcp.24858. |
3. | Sheng H, Rui XF, Sheng CJ, Li WJ, Cheng XY, Jhummon NP, Yu YC, Qu S, Zhang G, Qin L. A novel semisynthetic molecule icaritin stimulates osteogenic differentiation and inhibits adipogenesis of mesenchymal stem cells. Int J Med Sci. 2013;10: 782-9 |
4. | Shanthanagouda AH, Guo BS, Ye RR, Liang C, Chiang WL, Singaram G, Cheung KM, Zhang G (Corresponding author), Au WT (Corresponding author). Japanese Medaka: A Non-Mammalian Vertebrate Model for Studying Sex and Age-Related Bone Metabolism in vivo. PLoS One. 2014 Jan 5;9(2):e88165. |
5. | Zheng LZ, Liu Z, Lei M, Peng J, He YX, Xie XH, Man CW, Huang L, Wang XL, Fong DT, Xiao DM, Wang DP, Chen Y, Feng JQ, Liu Y, Zhang G (Corresponding author), Qin L (Corresponding author). Steroid-associated hip joint collapse in bipedal emus.PLoS One. 2013 Oct 21;8(10):e76797. |
6. | Liu B, Zhang H, Li J, Lu C, Chen G, Zhang G, Lu A, He X. Triptolide downregulates Treg cells and the level of IL-10, TGF-β, and VEGF in melanoma-bearing mice. Planta Med. 2013 Oct;79(15):1401-7. |
7. | Jiang M, Chen T, Feng H, Zhang Y, Li L, Zhao A, Niu X, Liang F, Wang M, Zhan J, Lu C, He X, Xiao L, Jia W, Lu A. Serum metabolic signatures of four types of human arthritis. J Proteome Res. 2013 Aug 2;12(8):3769-79. doi: 10.1021/pr400415a. |
8. | Guo B, Zhang B, Zheng L, Tang T, Liu J, Wu H, Yang Z, Peng S, He X, Zhang H, Yue KK, He F, Zhang L, Qin L, Bian Z, Tan W, Liang Z, Lu A, Zhang G. Therapeutic RNA interference targeting CKIP-1 with a cross-species sequence to stimulate bone formation. Bone. 2013;59:76-88. |
9. | Peng S, Zhang G (Co-first author), Zhang BT, Guo B, He Y, Bakker AJ, Pan X, Zhen W, Hung L, Qin L, Leung WN. The Beneficial Effect of Icaritin on Osteoporotic Bone is Dependent on the Treatment Initiation Timing in Adult Ovariectomized Rats. Bone. 2013 Feb 25. [Epub ahead of print] |
10. | Yang Z, Lu A, Wong BC, Chen X, Bian Z, Zhao Z, Huang W, Zhang G, Chen H, Xu M. Effect of Liposomes on the Absorption of Water-Soluble Active Pharmaceutical Ingredients Via Oral Administration. Curr Pharm Des. 2013 Apr 23. [Epub ahead of print] |
11. | Wang XL, Xie XH, Zhang G, Chen SH, Yao D, He K, Wang XH, Yao XS, Leng Y, Fung KP, Leung KS, Qin L. Exogenous phytoestrogenic molecule icaritin incorporated into a porous scaffold for enhancing bone defect repair. J Orthop Res. 2013 Jan;31(1):164-7. |
12. | Xu Q, Bauer R, Hendry BM, Fan TP, Zhao Z, Duez P, Simmonds MS, Witt CM, Lu A, Robinson N, Guo DA, Hylands PJ. The quest for modernisation of traditional Chinese medicine. BMC Complement Altern Med. 2013 Jun 13;13:132. |
13. | Liang F, Li L, Wang M, Niu X, Zhan J, He X, Yu C, Jiang M, Lu A (Corresponding Author). Molecular network and chemical fragment-based characteristics of medicinal herbs with cold and hot properties from Chinese medicine. J Ethnopharmacol. 2013 May 20. |
14. | Wang LY, Chan KW, Yuwen Y, Shi NN, Han XJ, Lu A (Corresponding Author). Expert consensus on the treatment of hypertension with chinese patent medicines. Evid Based Complement Alternat Med. 2013;2013:510146. |
15. | Dai J, Fang J, Sun S, Chen Q, Cao H, Zheng N, Zhang Y, Lu A. ZHENG-Omics Application in ZHENG Classification and Treatment: Chinese Personalized Medicine. Evid Based Complement Alternat Med. 2013;2013:235969. |
16. | Yang Z, Lu A, Wong BC, Chen X, Bian Z, Zhao Z, Huang W, Zhang G, Chen H, Xu M. Effect of Liposomes on the Absorption of Water-Soluble Active Pharmaceutical Ingredients Via Oral Administration. Curr Pharm Des. 2013 Apr 23. [Epub ahead of print] |
17. | Liu C, Zhang Y, Kong X, Zhu L, Pang J, Xu Y, Chen W, Zhan H, Lu A, Lin N. Triptolide Prevents Bone Destruction in the Collagen-Induced Arthritis Model of Rheumatoid Arthritis by Targeting RANKL/RANK/OPG Signal Pathway. Evid Based Complement Alternat Med. 2013;2013:626038. doi: 10.1155/2013/626038. |
18. | Lu C, Liu X, Ding X, Chen X, Fan H, Liu Y, Xie N, Tan Y, Ko J, Zhang W, Lu A (Corresponding Author). A Metabolomics Profiling Study in Hand-Foot-and-Mouth Disease and Modulated Pathways of Clinical Intervention Using Liquid Chromatography/Quadrupole Time-of-Flight Mass Spectrometry. Evid Based Complement Alternat Med. 2013; 2013:647452. |
19. | Zha Q, Lin S, Zhang C, Chang C, Xue H, Lu C, Jiang M, Liu Y, Xiao Z, Liu W, Shang Y, Chen J, Wen M, Lu A (Corresponding Author). Xiaoqinglong granules as add-on therapy for asthma: latent class analysis of symptom predictors of response. Evid Based Complement Alternat Med. 2013;2013:759476. doi: 10.1155/2013/759476. |
20. | Li X, Zhang C, Shi Q, Yang T, Zhu Q, Tian Y, Lu C, Zhang Z, Jiang Z, Zhou H, Wen X, Yang H, Ding X, Liang L, Liu Y, Wang Y,Lu A (Corresponding Author). Improving the efficacy of conventional therapy by adding and rographolide sulfonate in the treatment of severe hand, foot, and mouth disease: a randomized controlled trial. Evid Based Complement Alternat Med.2013;2013:316250. doi:10.1155/2013/316250. |
21. | Xie XH, Wang XL, Zhang G, He YX, Leng Y, Tang TT, Pan X, Qin L. Biofabrication of a PLGA-TCP-based porous bioactive bone substitute with sustained release of icaritin. J Tissue Eng Regen Med. 2012 Dec 18. |
22. | Baosheng Guo, Songlin Peng, Chao Liang, Xiaojuan He, Cheng Xiao, Cheng Lu, Miao Jiang, Hongyan Zhao, Aiping Lu (Corresponding Author), Ge Zhang (Corresponding Author). Recent developments in bone anabolic therapy for osteoporosis.Expert Review of Endocrinology & Metabolism. 2012 Nov;7(6): 677-685 |
23. | Zhu GY, Wong BC, Lu A, Bian ZX, Zhang G, Chen HB, Wong YF, Fong WF, Yang Z. Alkylphenols from the roots of Ardisia brevicaulis induce G1 arrest and apoptosis through endoplasmic reticulum stress pathway in human non-small-cell lung cancer cells. Chem Pharm Bull (Tokyo). 2012;60(8):1029-36. |
24. | Wei F, Moore DC, Li Y, Zhang G, Wei X, Lee JK, Wei L. Attenuation of osteoarthritis via blockade of the SDF-1/CXCR4 signaling pathway. Arthritis Res Ther. 2012 Jul 31;14(4):R177 |
25. | Zhu HM (Co-first author), Qin L (Co-first author), Garnero P (Co-first author), Genant HK (Co-first author), Zhang G(Co-first author), Dai K, Yao X, Gu G, Hao Y, Li Z, Zhao Y, Li W, Yang J, Zhao X, Shi D, Fuerst T, Lu Y, Li H, Zhang X, Li C, Zhao J, Wu Q, Zhao SJ. The first multicenter and randomized clinical trial of herbal Fufang for treatment of postmenopausal osteoporosis.Osteoporos Int. 2012 Apr;23(4):1317-27. |
26. | He YX, Liu Z, Pan XH, Tang T, Guo BS, Zheng LZ, Xie XH, Wang XL, Lee KM, Li G, Cao YP, Wei L, Chen Y, Yang ZJ, Hung LK, Qin L, Zhang G (Corresponding Author). Deletion of estrogen receptor beta accelerates early stage of bone healing in a mouse osteotomy model. Osteoporos Int. 2012 Jan;23(1):377-89. |
27. | Li J, Lu C, Jiang M, Niu X, Guo H, Li L, Bian Z, Lin N, Lu A (Corresponding Author). Traditional chinese medicine-based network pharmacology could lead to new multicompound drug discovery. Evid Based Complement Alternat Med. 2012;2012:149762. |
28. | Yang H, Yang J, Wen Z, Zha Q, Nie G, Huang X, Zhang C, Lu A (Corresponding Author), Jiang M, Wang X. Effect of combining therapy with traditional chinese medicine-based psychotherapy and herbal medicines in women with menopausal syndrome: a randomized controlled clinical trial. Evid Based Complement Alternat Med. 2012; 2012:354145. |
29 | Jiang M, Lu C, Chen G, Xiao C, Zha Q, Niu X, Chen S, Lu A (Corresponding Author). Understanding the molecular mechanism of interventions in treating rheumatoid arthritis patients with corresponding traditional chinese medicine patterns based on bioinformatics approach. Evid Based Complement Alternat Med. 2012;2012:129452. |
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